iosr-JDMS   Volume-15 ~ Issue-4 ~ April-2016

Abstract: Breast cancer is the second most leading cause of cancer mortality in Asian countries. The prognosis depends on variable clinical and tumor related factors. Assessment of molecular markers in breast cancer i.e. estogen, progesterone receptors and Her2 neu is strongly recommended to provide best therapeutic options. The aim of this study is to determine the correlation present between molecular markers and other prognostic factors in carcinoma breast. A total 100 cases of invasive duct cancers were included in this study..............

Keywords: Breast Cancer, Estrogen, Her2/neu, Progesterone

[1]. Indian Journal Cancer 2008.Vol 45,Issue 1.
[2]. Rosai and Ackerman's Surgical Pathology,Rosai,10th edition,2011.
[3]. Quiet CA , Ferguson DJ et al : Natural history of node negative breast cancer , astudy of 826 patients with longterm followup. J of Clinical Oncol 13 : 1144-1151, 1995.
[4]. Robbins and Cotran; Pathologic Basis of Disease,8th Edition,p 1084-86.
[5]. McGuire WL et al: Current status of estogen receptor in human breast cancer.Cancer 36 : 638-44,1975

Abstract: Linga Chendhuram (LC) is a traditional Siddha Sastric formulation used in the management of fever at the dosage 65 mg with the adjuvant Honey. It is prepared through the special oxidation of purified Lingam (Cinnabar – Mercuric sulphide) using juice of Citrullus colocynthis as narrated in Siddha Materia Medica. Physicochemical characterization of LC has been carried out using analyses mentioned in the Chendhuram protocol of Pharmacopoeial Laboratory for Indian Medicine........

Keywords: Cinnabar, Chendhuram, Fever, Lingam, Siddha

[1]. B Tie, W. Qi, and G. Chen, Determination of soluble mercury contents in Chinese traditional patent medicines for children, Zhongguo Zhong Yao Za Zhi, 15(10), 1990, 602– 639.
[2]. E O Espinoza, M. J. Mann, and B. Bleasdell, Arsenic and mercury in traditional Chinese herbal balls, The New England Journal of Medicine, 333(12), 1995, 803–804.
[3]. A D Hardy, H. H. Sutherland, R. Vaishnav, and M. A.Worthing, A report on the composition of mercurials used in traditional medicines in Oman, Journal of Ethnopharmacology, 49(1), 1995, 17–22.
[4]. R. Thiagarajan, Gunapadam-Thathu Jeeva vaguppu, 4th edition, 2004; Directorate of Indian Medicine & Homeopathy, Govt. of Tamil Nadu
[5]. K.N. Kuppuswamy and K.S. Utamarayan, Siddha pharmacopoeia (In Tamil), Parinilyam, Madras, 1987.

Abstract: Objectives: To analyze the role of CT alone in the evaluation of Orbital Tumors. Material And Methods: 50 patients presenting with orbital masses were evaluated for CT scan Orbits. Role of CT was evaluated in characterizing the precise location and extension of the lesions causing proptosis. Final diagnosis was made based on the histopathology, operative findings and clinical outcome.......

Keywords: Computed Tomography; Tumors ,Pseudo Tumors,Lymphoma, Glioma .

[1]. Shields JA. Diagnosis and management of orbital tumors.Philadelphia: Saunders; 1989:89-388.
[2]. Kanski JJ. Clinical ophthalmology. A systematic approach.4th ed. Oxford: Butterworth Heinemann; 1999:574-584.
[3]. Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumours and simulating lesions. The 2002 Montgomery Lecture: Part 1. Ophthalmology 2004;111:997-1008.
[4]. Hammerschlag SB, Hesselink JR, Weber AL. Computed tomography of the eye and orbit. Norwalk: Appleton CenturyCrofts; 1983:24-25.
[5]. De Potter P, Shields JA, Shields CL. MRI of the eye and orbit. New York: Lippincott Williams and Wilkins; 1995:8-17.

Abstract: Paraneoplastic Cushing's syndrome is a rare cause of endogenous hypercortisolism . It is due to ectopic ACTH secretion by a non-pituitary endocrine tumor. It can precede, accompany or follow the discovery of the tumor. The differential diagnosis of Cushing's disease is not evident.We report the case of a man of 20 years old , admitted on suspicion of cushing's syndrome. Somatic exam found clear signs of hypercortisolism without melanodermia or high blood pressure . Carbohydrate and ionic level were normally........

Keywords: Paraneoplastic Cushing's syndrome, melanodermia, hypokalemia, Catheterization of petrosal sinus , bronchial carcinoid

[1]. Isidori AM, Lenzi A. Ectopic ACTH Syndrome. Arq Bras Endocrinol Metab 2007;51:1217-25.
[2]. Ankotche. A, Raffin-Sanson. M. L, Mosnier-Pudard. H, Bertagna. X , Luton. J. P.Secretion ectopique d'ACTH : Une entité hétérogène.Presse Med 1997 ; 26 : 1330-3.
[3]. BROWN WH – « A case of pluriglandular syndrome (diabetes of bearded women) » – Lancet, 1928 (2), 1022-3
[4]. Meador CK, Liddle GW(1962) Cause of Cushing's syndrome in patients with tumours arising from non-endocrine tissue. J Clin Endocrinol Metab 22:693.
[5]. Bertagna. X , Nicholson. W. E, Mount. C. D, Orth. DN , Girard. F, Bricaire. H.Secretion ectopique d'ACTH et de peptides apparentées (LPHs, Bendorphine, « 16K) mise en evidence d'un précurseur commun.Horm Res 1980 ; 13 : 291-01.

Abstract: Background: Schizophrenia cause distressing consequences for afflicted patients, their family members, and others involved in their care and support, as well as society at large in terms of lost productivity and cost of providing treatment, housing, and financial assistance. Aim & objective: To study socio-demographic variables and other psychosocial factors associated with the relapse in schizophrenic patient.......

Keywords: Sociodemographic Profile; Relapse; Remission; Psychosocial factor.

[1]. D. Robinson, M. G. Woerner, J. M. Alvir, R. Bilder, R. Goldman, S. Geisler, A. Koreen, B. Sheitman, M. Chakos, D. Mayerhoff
and J. A. Lieberman, "Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder,"
Arch Gen Psychiatry, vol. 56, no. 3, pp. 241-247, 1999.
[2]. J. M. Kane, "Treatment strategies to prevent relapse and encourage remission," J Clin Psychiatry, vol. 68 Suppl 14, pp. 27-30, 2007.
[3]. M. G. Harris, L. P. Henry, S. M. Harrigan, R. Purcell, O. S. Schwartz, S. E. Farrelly, A. L. Prosser, H. J. Jackson and P. D.
McGorry, "The relationship between duration of untreated psychosis and outcome: an eight-year prospective study," Schizophr Res,
vol. 79, no. 1, pp. 85-93, 2005.
[4]. A. American Psychiatric, A. American Psychiatric and D.-I. Task Force on, Diagnostic and statistical manual of mental disorders :
DSM-IV-TR, American Psychiatric Association, Washington, DC, 2000.
[5]. G. Chabungbam, A. Avasthi and P. Sharan, "Sociodemographic and clinical factors associated with relapse in schizophrenia,"
Psychiatry Clin Neurosci, vol. 61, no. 6, pp. 587-593, 2007.

Abstract: Objective: To evaluate the role of Cord Blood Nucleated Red Blood Cell (NRBC) Count as a predictor of the Birth Asphyxia in full term newborns. Methods: A hospital based prospective observational case control study was carried out at SNCU, Department of Pediatrics, RNT Medical College, Udaipur (Raj.) from March 2015 to September 2015. Total 100 full term newborns including 50 asphyxiated (cases) and 50 non asphyxiated (controls) were enrolled for the study........

Keywords: APGAR Score, Hypoxic Ischemic Encephalopathy, Nucleated Red Blood Cells, Perinatal/Birth Asphyxia, Umbilical Cord Blood pH.

[1]. National Neonatal and Perinatal Database Report. 2002- 2003:1-58.
[2]. World Health Organization. Neonnatal and Perinatal Mortality; Country, Regional and Global estimates, 2004; WHO,Geneva.
2006; 1-25.
[3]. Namasivayam A, Waldemar A C. Hypoxic Ischemic Encephalopathy. In: Kliegman RM, Stanton BF, St Geme III JW, Schor NF,
eds. Nelson Text Book of Pediatrics. 20th ed. Elseviers Saunders Philadelphia; 2015:838-842.
[4]. Green DW, Hendon B, Mimouni FB. Nucleated Erythrocytes And Intraventricular Hemorrhage In Preterm Neonates. Pediatrics
1995; 96 (3): 475–8.
[5]. Forestier F, DaVos F, Catherine N, et al. Developmental Hematopoiesis In Normal Human Fetal Blood. Blood 1991;77:2360–3.

Abstract: Background: Mumps is an acute viral self -limiting disease which is highly contagious transmitted by droplet spread or by close personal contact.The classic mumps illness is characterized by fever and swelling of the parotid glands and may lead to various complications. Despite of availability of effective vaccination mumps still remains very prevalent.......

Keywords: Mumps, Immunization, Orchitis

[1]. Vashishtha ,etal. Burden of mumps in india and vaccination strategies Indian pediatric volume 52 – june 15 ,2015.
[2]. World Health Organization position paper mumps virus vaccines, wkly epidemiol rec, 2007;7:51:60
[3]. Litman N, Baum SG Mumps virus. In: Mandell GL Bennets Je Dolin R(eds).Principles and Practice of Infectious Diseases; 6th ed,
Philadephia ; Churchill Livingstone,2003-2008
[4]. Sanjaya N Senanayake , Mumps a resurgent disease with protean manifestations . MJA 2008;189: 456-459
[5]. Bhatnagar et al. Introducing combined measles, mumps and rubella vaccine in chandigarh, India.

Abstract: 90 patients of decompensated chronic liver diseases were selected and randomised to treat with either lactulose or rifaximin or both lactulose and rifaximin (30 patients in each group) for 7 days. Pretreatment and post-treatment arterial blood ammonia level were measured amongst each group of treatment. The study was to review the comparison of the effectiveness of Rifaximin.......

Keywords: Chronic, Liver, Disease ,Blood, Ammonia

[1]. Schfer DF, Jones EA. Hepatic encephalopathy. In Zakim D, Boyer TD, editors. Hepatology. A Textbook of liver disease .
Philadelphia: W. B. Saunders, 1990 : 447-460
[2]. Abou-Assi S, Vlahcevic ZR. Hepatic encephalopathy. Metabolic consequence of cirrhosis often is reversible. Postgrad. Med. 2001;
109: 52-54, 57-60, 63-65.
[3]. Butterworth RF. Neurotransmitter dysfunction in hepatic encephalopathy : new approaches and new findings. Metabolic Brain
Disease 2001;16:55-65.
[4]. Fitz G. Hepatic encephalopathy, hepatopulmonary syndrome, coagulopathy and other complication of chronic liver diseases. In:
Feldman M, Friedman LS, Sleisenger MH, editors. Sleisenger and Fordtrans Gastrointestinal and liver ds. 7th. Ed. Philadelphia:
Saunders, 2002
[5]. Schiano TD. Complication of chronic liver disease. In Friedman S, Grendell J, Macquaid K, editors. Current diagnosis and
treatment in Gastroenterology. 2nd. Ed. Lange Current Series, 2002

Abstract: Poisoning is a common medical emergency in childhood and one of the important causes of hospital admission and also of death. An institution based cross-sectional observational study was conducted in B.S. Medical College and hospital, Bankura, West Bengal, India. Among 89 cases of poisoning studied, 62 cases were between 1 to 3 years of age. Overall mortality was 6.67% and 8.89% cases required intensive care support. This study helps us to know the clinico-epidemiological profile of poisoning in children in this part of the country.

Keywords: Poisoning, cross-sectional study, observational study, profile of poisoning, India.

[1]. Lam LT, childhood and adolescent poisoning in NSW Australia: an analysis of age, sex, geographic, and poison types, injury prevention 2003; 9: 338-342.
[2]. Basu M, Kundu T K, Dasgupta M K, Das D K, Saha I, Poisoning, Sting and Bites in children-what is new ? An experience from a tertiary care hospital in Kolkata Indian Journal of Public Health Vol. 53 No4 October-December.2009.
[3]. Sitaram S, Sharma U, Saxena S. Accidental poisoning in children. Indian Pediatr 1985; 22: 757-760.

[4]. Singh S, Singhi S, Sood NK, Kumar L, Walia BNS. Changing pattern of childhood poisoning (1970-1989): experience of a large north Indian hospital. Indian Pediatr 1995; 32: 331-6.
[5]. Khadgawat R, Garg P, Bansal P, Arya A, Choudhary B. Accidental poisoning. Indian pediatrics. Volume-31 December 1999:1555-1557.

Abstract: Proximal femoral fractures are most common in old and middle age patients. The dynamic hip screw (DHS) is the most common extramedullary implant used but the failure rate for a DHS is reported to be as high as 21%[1) proximal femoral nail (PFN)system was designed to overcome the above mentioned limitations with has an additional anti-rotational screw (hip pin) for unstable trochanteric and subtrochanteric fractures.The present study includes 50 patients of proximal femoral fractures, treated with Proximal Femoral Nail from April' 2013 to May' 2014 at the Department of Orthopedics, Sir Sayajirao General Hospital, Vadodara........

Keywords: Orthopedics, Proximal femoral fracture, proximal femoral nail

[1]. Werner-Tutschku W, Lajtai G, Schmiedhuber G et al. Intra-und perioperative Komplikationen bei der Stabilisierung von per-und subtrochantären Femurfracturen mittels PFN. Unfallchirurg 2002; 105: 881-885.
[2]. Herrera A, Domingo LJ, Calvo A, Martinez A, Cuenca J. A comparative study of trochanteric fractures treated with the Gamma nail or the proximal femoral nail. Int Orthop 2002; 26: 365–9.
[3]. Zafiropoulos G, Pratt DJ. Fractured Gamma nail. Injury 1994; 25: 331–6.
[4]. Schipper IB, Bresina S, Wahl D, Linke B, Van Vugt AB, Schneider E. Biomechanical evaluation of the proximal femoral nail. Clin Orthop Relat Res 2002; 405: 277–86.
[5]. Radford PJ, Needoff M, Webb JK. A prospective randomized comparison of the dynamic hip screw and the gamma locking nail. J Bone Joint Surg 1993 ; 75-B : 789-79.

Abstract: Currently, we aimed to assess serum testosterone and DHEA-S among oligo and azoospermia patients. The study included 60 patients with oligospermia, 60 with azoospermia and 60 normospermia as control. Serum testosterone and DHEA-S levels were measured using competitive ELISA. BMI was calculated from weight/kg divided height/m2........

Keywords: Testosterone, DHEA-S, Oligospermia, Azoospermia, Male infertility

Rajni Bala, Vikas Chandra Gupta, Vijay Kumar. A study to evaluate effect of yashad bhasm in oligospermia. World journal of
pharmacy and pharmaceutical sciences 2015; 4 (1): 516-520.
[2]. Jonathan Jarow, Mark Sigman, Peter N. kolettis, Larry R. Lipshultz, R. Dale McClure, Ajay K. Nangia, Cathy Kim Naughton, Gail
S. Prins, Jay I. Sandlow, and Peter N. Schlegel. Evaluation of the Azoospermic male: AUA best practice statement, American
Urological Association Education and Research 2010. 4-6.
[3]. Ashok Agarwal, Aditi Mulgund, Alaa Hamada and Michelle Renee Chyatte. A unique view on male infertility around the globe,
Reproductive Biology and Endocrinology 2015. 13 (37): 1-9
[4]. Steven Palter, Diagnostic evaluation of the infertile male: committee opinion, American society for reproductive medicine 2015;
103 (3): 18-25.
[5]. Nazar M. Abdalla, Sudanese male fertility and infections. Sci Parasitol 2011; 12 (3):123-129.